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Antigenic Specificity | HLA-DPB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HLA-DPB1 antibody detects endogenous levels of total HLA-DPB1. Description: HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP mol |
Immunogen | Immunogen: A synthesized peptide derived from human HLA-DPB1 Subcellular Location: Cell Membrane. Endoplasmic Reticulum Membrane. Golgi Apparatus > Trans-Golgi Network Membrane. Endosome Membrane. Lysosome Membrane. The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation. |
Other Names | [D6S221E; DMA; DMB; DP beta 1; DP beta 1 chain; DP(W4) beta chain; DPB 1; DPB1; DPB1_HUMAN; DRB; H2Ea; HLA class II histocompatibility antigen; HLA class II histocompatibility antigen DM beta chain; HLA class II histocompatibility antigen, DP beta 1 chain; HLA class II histocompatibility antigen, DP(W4) beta chain; HLA DMB; HLA DP1A; HLA DPB1; HLA SB alpha chain; HLA-A; HLA-A histocompatibility type; HLA-DP; HLA-DP histocompatibility type, beta-1 subunit; HLA-DP1B; HLA-DPB; HLA-DPB1; HLADM; HLADP1B; HLASB; HLASB histocompatibility type; Human MHC class II HLA SB alpha; LA class II histocompatibility antigen DP alpha 1 chain; Major histocompatibility complex class II; Major histocompatibility complex class II DP alpha 1; Major histocompatibility complex class II DP beta 1; Major histocompatibility complex, class I, A; MHC class II antigen DMB; MHC class II antigen DPB1; MHC class II DP3 alpha; MHC class II DPA1; MHC class II HLA-DP-beta-1; MHC DPB1; MHC HLA DPB1; PLT1; Primed lymphocyte test 1; RING6; RING7] |
Gene, Accession # | [HLA-DPB1], Gene ID: 3115, NCBI: NP_002112.3, UniProt: P04440 |
Catalog # | MBS9607065 |
Price | $240, $280 |
Order / More Info | HLA-DPB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |