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Antigenic Specificity | PFN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using PFN1 antibody. The dynamic polymerization and depolymerization of actin filaments, a process governed by external and internal signaling events, is vital for cell motility (immune cell function, migration, invasion, metastasis, angiogenesis), cell division and adhesion. Among the many regulators of actin dynamics are profilins. Profilins are conserved actin binding proteins that affect the rate of actin polymerization by binding actin monomers and promoting the exchange of ADP for ATP (reviewed in 1). Profilins bind to proteins involved in the regulation of actin dynamics including palladin (2), dynamin-1 (3), VASP (4) and N-WASP (5). In mice, knockout of the ubiqui |
Immunogen | Immunogen: Recombinant protein of human PFN1 |
Other Names | [profilin-1; Profilin-1; profilin-1; profilin 1; Epididymis tissue protein Li 184a; Profilin I], [PFN1; PFN1; ALS18] |
Gene, Accession # | [PFN1], Gene ID: 5216, NCBI: NP_005013.1, UniProt: P07737 |
Catalog # | MBS419573 |
Price | $385 |
Order / More Info | PFN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |