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Antigenic Specificity | PPL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [Periplakin; Periplakin; periplakin; 190 kDa paraneoplastic pemphigus antigen; 195 kDa cornified envelope precursor protein; periplakin; 190 kDa paraneoplastic pemphigus antigen; 195 kDa cornified envelope precursor protein], [PPL; PPL; KIAA0568] |
Gene, Accession # | [PPL], Gene ID: 5493, NCBI: O60437.4, UniProt: O60437 |
Catalog # | MBS129991 |
Price | $200, $275, $430 |
Order / More Info | PPL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |