SPIN1 - N-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SPIN1 - N-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, dog, human, mouse, porcine, rabbit, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against SPIN1. It was validated on Western BlotTarget Description: SPIN1 is a chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway dowstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006).It may play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic re |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SPIN1 |
| Other Names | [spindlin-1; Spindlin-1; spindlin-1; spindlin 1; Ovarian cancer-related protein] |
| Gene, Accession # | [SPIN1], Gene ID: 10927, NCBI: NP_006708, UniProt: Q9Y657 |
| Catalog # | MBS3210686 |
| Price | $335 |
| Order / More Info | SPIN1 - N-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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