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Antigenic Specificity | RAB11FIP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RAB11FIP2 antibody detects endogenous levels of total RAB11FIP2. Function: A Rab11 effector binding preferentially phosphatidylinositol 3, 4, 5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.Subunit Structure: Homooligomerizes in a Rab11-independent manner. Forms a heterool |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane. Recycling Endosome Membrane. Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (89%) |
Other Names | [KIAA0941; NRip11; RAB11 family interacting protein 2 (class I); Rab11 family-interacting protein 2; RAB11 FIP2 long isoform; Rab11-FIP2; RAB11FIP2; RFIP2; RFIP2_HUMAN] |
Gene, Accession # | [RAB11FIP2], Gene ID: 22841, NCBI: NP_001317096.1, UniProt: Q7L804 |
Catalog # | MBS9605824 |
Price | $240, $280 |
Order / More Info | RAB11FIP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |