Phospho-eIF4B (Thr420) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-eIF4B (Thr420) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mousepredicted: bovine, horse, sheep, rabbit, dog, Xenopus |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-eIF4B (Thr420) Antibody detects endogenous levels of eIF4B only when phosphorylated at Thr420. Description: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.Post Translational Modifications: Phosphorylated at Ser-422 by RPS6KA1 and RPS6KB1; phosphorylation enhances the affinity of EIF4B for the EIF3 complex.Subunit Structure: Self-associates and interacts with EIF3 p170 subunit. |
| Immunogen | Immunogen: A synthesized peptide derived from human eIF4B around the phosphorylation site of Thr420. |
| Other Names | [2310046H11Rik; AL024095; C85189; EIF 4B; eIF-4B; EIF4B; Eukaryotic initiation factor 4B; Eukaryotic translation initiation factor 4B; IF4B_HUMAN; PRO1843] |
| Gene, Accession # | [eIF4B], Gene ID: 1975, NCBI: NP_001408.2, UniProt: P23588 |
| Catalog # | MBS9610629 |
| Price | $225, $280, $340 |
| Order / More Info | Phospho-eIF4B (Thr420) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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