Human GALR1 / Galanin Receptor 1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human GALR1 / Galanin Receptor 1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | Gibbon, gorilla, human. predicted reactivity: monkey (at least 90% immunogen sequence identity) |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.05 mg |
| Concentration | 1 mg/ml |
| Applications | Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human GALR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SSTR5 (50%). GalR1 is a Galanin Receptor that mediates the effects of the peptide galanin in a wide variety of tissues. Unlike GalR2, the primary signaling mechanism of GalR1 is by inhibiting adenylate cyclase through Gi. GalR1 regulates the GnRH neuroendocrine axis with its expression in POMC neurons. Pathogens like E Coli can cause diarrhea by increasing expression of Galanin Receptor 1 in the epithelial cells lining the colon, resulting in increased secretion of colonocyte chloride and fluid. |
| Immunogen | Immunogen Description: Synthetic 18 amino acid peptide from N-terminal extracellular domain of human GALR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (94%); Dog (89%); Panda, Horse (83%). |
| Other Names | [GALR1 / Galanin Receptor 1 (N-Terminus) IHC-plus; GALR1; Galanin receptor type 1; Galanin receptor 1; Galanin receptor galr1; Galanin-1 receptor; GALNR1; Gal receptor 1; Gal-r1; Galn1r; Gal-1 receptor; GAL1-R; Galanin r1 receptor; GALNR; GALR-1; Hugal 1-r; Human GALR1; Galanin Receptor 1], [GALR1; GALR1; GALNR; GALNR1; GALNR; GALNR1; GAL1-R; GALR-1] |
| Gene, Accession # | [GALR1], Gene ID: 2587, NCBI: NP_001471.2, UniProt: P47211 |
| Catalog # | MBS243341 |
| Price | $530 |
| Order / More Info | Human GALR1 / Galanin Receptor 1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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