Crk II (Phospho Tyr221) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Crk II (Phospho Tyr221) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, monkey |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.03 mL, 0.1 mL, 0.2 mL |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-Crk II (Y221) Polyclonal Antibody detects endogenous levels of Crk II protein only when phosphorylated at Y221. CRK encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of CRK (CRK proto-oncogene, adaptor protein) has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with di |
| Immunogen | Immunogen: Synthesized peptide derived from human Crk II around the phosphorylation site of Y221 |
| Other Names | [Rabbit Crk II (phospho Tyr221); Adapter molecule crk; Proto-oncogene c-Crk; p38] |
| Gene, Accession # | [CRK], Gene ID: 1398, NCBI: NP_005197.3, UniProt: P46108 |
| Catalog # | MBS9701191 |
| Price | $130, $220, $325 |
| Order / More Info | Crk II (Phospho Tyr221) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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