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Antigenic Specificity | PI4K2A (PI4K II) (N-term), 1-30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 1.27 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PI4K2A (PI4K II) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PI4K2A (PI4K II). Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs. PI4K II is activated by detergent and inhibited by adenosine. Overexpression of PI4KII in COS-7 cells increases synthesis of PtdIns4P. Some cells overexpressing PI4KII have scattered or no perinuclear Golgi. Knockdown of PI4KII by RNA interference (RNAi) does not disrupt t |
Immunogen | n/a |
Other Names | [Phosphatidylinositol 4-kinase type 2-alpha; Phosphatidylinositol 4-kinase type II-alpha; PI4K2A] |
Gene, Accession # | [PI4K2A], Gene ID: 55361, NCBI: NP_060895.1, UniProt: Q9BTU6 |
Catalog # | MBS9212614 |
Price | $165, $370 |
Order / More Info | PI4K2A (PI4K II) (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
Product Specific References | Wang, Y.J., et al., Cell 114(3):299-310 (2003). Minogue, S., et al., J. Biol. Chem. 276(20):16635-16640 (2001). Barylko, B., et al., J. Biol. Chem. 276(11):7705-7708 (2001). Waugh, M.G., et al., Biochem. J. 373 (Pt 1), 57-63 (2003). |