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Antigenic Specificity | SFPQ - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against SFPQ. It was validated on Western Blot and immunohistochemistryTarget Description: SFPQ is DNA- and RNA binding protein. It is essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as an heteromer with NONO. It binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. It interacts with U5 snRNA. It may be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A. SFPQ may be involved in homologous DNA pairing. SFPQ is involved in transcriptional regulation. It binds the DNA sequence 5'-CTGAGTC-3' in the insulin-like gro |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SFPQ |
Other Names | [splicing factor, proline- and glutamine-rich; Splicing factor, proline- and glutamine-rich; splicing factor, proline- and glutamine-rich; splicing factor proline and glutamine rich; 100 kDa DNA-pairing protein; hPOMp100; DNA-binding p52/p100 complex, 100 kDa subunit; Polypyrimidine tract-binding protein-associated-splicing factor; PSF; PTB-associated-splicing factor] |
Gene, Accession # | [SFPQ], Gene ID: 6421, NCBI: NP_005057, UniProt: P23246 |
Catalog # | MBS3205326 |
Price | $290 |
Order / More Info | SFPQ - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |