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Antigenic Specificity | Mouse IL6ST |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta or CD130) is a transmembrane protein which is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and Oncostatin M (OSM). CD130/gp130 functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. CD130/gp130 plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. The receptor systems for IL |
Immunogen | Immunogen: Recombinant Mouse gp130/CD130/IL6ST protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
Other Names | [interleukin-6 receptor subunit beta isoform 3; Interleukin-6 receptor subunit beta; interleukin-6 receptor subunit beta; interleukin 6 signal transducer; CDw130; Interleukin-6 signal transducer; Membrane glycoprotein 130; gp130; Oncostatin-M receptor subunit alpha; CD_antigen: CD130] |
Gene, Accession # | [IL6ST ], Gene ID: 3572 |
Catalog # | MBS2544493 |
Price | $215, $330, $500 |
Order / More Info | Mouse IL6ST Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |