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Antigenic Specificity | XPO7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of XPO7 protein. Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribu |
Immunogen | Immunogen: Synthesized peptide derived from part region of human XPO7 protein |
Other Names | [Rabbit XPO7; Exportin-7; Exp7; Ran-binding protein 16] |
Gene, Accession # | [XPO7], Gene ID: 23039, NCBI: NP_055839.3, UniProt: Q9UIA9 |
Catalog # | MBS9711458 |
Price | $130, $220, $325 |
Order / More Info | XPO7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |