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Antigenic Specificity | Caspase-10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Caspase-10(CASP10) detection. Tested with WB, IHC-P in Human. Background: Caspase-10 is an enzyme that, in humans, is encoded by the CASP10 gene. The Caspase 10 gene contains 11 exons and spans about 48 kb. This gene is mapped to 2q33.1. It is transcribed in the centromere-to-telomere direction.This gene encodes a protein that is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CASP10 (220-236aa VKTFLEALPRAAVYRMN). |
Other Names | [Caspase-10(CASP-10); caspase 10, apoptosis-related cysteine peptidase; ALPS 2; ALPS2; Apoptosis related cysteine peptidase; Apoptotic protease Mch 4; Apoptotic protease Mch-4; CASP 10; CASP-10; CASP10; CASP10 protein; CASPA_HUMAN; Caspase 10 apoptosis related cysteine peptidase; Caspase 10 apoptosis related cysteine protease; Caspase-10 subunit p12; Caspase10; FADD Like Ice 2; FADD like ICE2; Fas Associated Death Domain Protein; FAS associated death domain protein interleukin 1B converting enzyme 2; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE 2; FLICE2; ICE Like Apoptotic Protease 4; ICE-like apoptotic protease 4; Interleukin 1B Converting Enzyme 2; MCH 4; MCH4], [CASP10; CASP10; MCH4; ALPS2; FLICE2; MCH4; CASP-10; FLICE2] |
Gene, Accession # | [CASP10], Gene ID: 843, NCBI: Q92851.3, UniProt: Q92851 |
Catalog # | MBS175684 |
Price | $315 |
Order / More Info | Caspase-10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |