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Antigenic Specificity | JMJD6 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of JMJD6(N-terminus) and does not cross-react with related proteins. UniPort Summary Function: Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Acts as a regulator of RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. In addition to peptidyl-lysine 5-dioxygenase activity, may act as a RNA hydroxylase, as suggested by its ability to bind single strand RNA. Also acts as an arginine demethylase which demethylates histone H3 at ?Arg-2? (H3R2me) and histone H4 at ?A |
Immunogen | Immunogen: Purified recombinant human JMJD6(N-terminus) fragments expressed in E Coli. Cellular Localization: Nucleus |
Other Names | [jumonji domain containing 6; Lysyl-hydroxylase JMJD6; Phosphatidylserine receptor; PTDSR; KIAA0585; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; PSR; Peptide-lysine 5-dioxygenase JMJD6; Protein PTDSR], [PSR; PTDSR; PTDSR1] |
Gene, Accession # | [JMJD6], Gene ID: 23210, NCBI: NP_001074930.1, UniProt: Q6NYC1 |
Catalog # | MBS857732 |
Price | $300 |
Order / More Info | JMJD6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |