JMJD6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityJMJD6
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formataffinity purified
Size0.1 mg
Concentrationn/a
Applicationsn/a
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DescriptionThis antibody detects endogenous levels of JMJD6(N-terminus) and does not cross-react with related proteins. UniPort Summary Function: Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Acts as a regulator of RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. In addition to peptidyl-lysine 5-dioxygenase activity, may act as a RNA hydroxylase, as suggested by its ability to bind single strand RNA. Also acts as an arginine demethylase which demethylates histone H3 at ?Arg-2? (H3R2me) and histone H4 at ?A
ImmunogenImmunogen: Purified recombinant human JMJD6(N-terminus) fragments expressed in E Coli. Cellular Localization: Nucleus
Other Names[jumonji domain containing 6; Lysyl-hydroxylase JMJD6; Phosphatidylserine receptor; PTDSR; KIAA0585; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; PSR; Peptide-lysine 5-dioxygenase JMJD6; Protein PTDSR], [PSR; PTDSR; PTDSR1]
Gene, Accession #[JMJD6], Gene ID: 23210, NCBI: NP_001074930.1, UniProt: Q6NYC1
Catalog #MBS857732
Price$300
Order / More InfoJMJD6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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