ITGA8 (C-term), 1025-1053 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityITGA8 (C-term), 1025-1053
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.29
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis ITGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1053 amino acids from the C-terminal region of human ITGA8. Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.
Immunogenn/a
Other Names[Integrin alpha-8; Integrin alpha-8 heavy chain; Integrin alpha-8 light chain; ITGA8]
Gene, Accession #[ITGA8], Gene ID: 8516, NCBI: NP_003629.1, UniProt: P53708
Catalog #MBS9209958
Price$165, $370
Order / More InfoITGA8 (C-term), 1025-1053 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBenoit, Y.D., et al. Biochem. Biophys. Res. Commun. 399(3):434-439(2010) Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009) Benoit, Y.D., et al. Biol. Cell 101(12):695-708(2009) Sato, Y., et al. J. Biol. Chem. 284(21):14524-14536(2009) Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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