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Antigenic Specificity | ITGA8 (C-term), 1025-1053 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.29 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ITGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1053 amino acids from the C-terminal region of human ITGA8. Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons. |
Immunogen | n/a |
Other Names | [Integrin alpha-8; Integrin alpha-8 heavy chain; Integrin alpha-8 light chain; ITGA8] |
Gene, Accession # | [ITGA8], Gene ID: 8516, NCBI: NP_003629.1, UniProt: P53708 |
Catalog # | MBS9209958 |
Price | $165, $370 |
Order / More Info | ITGA8 (C-term), 1025-1053 Antibody from MYBIOSOURCE INC. |
Product Specific References | Benoit, Y.D., et al. Biochem. Biophys. Res. Commun. 399(3):434-439(2010) Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009) Benoit, Y.D., et al. Biol. Cell 101(12):695-708(2009) Sato, Y., et al. J. Biol. Chem. 284(21):14524-14536(2009) Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009) : |