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Antigenic Specificity | P2X3 Receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The P2X3 receptor belongs to the ligand-gated ion channel P2X family, that consists of seven receptor subtypes named P2X1-P2X7 and is activated by extracellular ATP. 1, 2, 3 All P2X subunits, with the exception of P2X6, can assemble to form homomeric or heteromeric functional channels.4-5 The different P2X receptors show distinct expression patterns. P2X1-6 has been found in the central and peripheral nervous system, while the P2X7 receptor is predominantly found in cells of the immune system. The P2X3 receptor is highly expressed on nociceptive sensory neurons in dorsal root ganglia (DRG) as a homomer or as a heteromer (P2X3/P2X2). ATP released from damaged cells activates the P2X3 receptor to initiate nociceptive signals.6, 7 Involvement |
Immunogen | Immunogen: Peptide (C)VEKQSTDSGAYSIGH corresponding to residues 383-397 of rat P2X3 (Accession P49654). |
Other Names | [P2X purinoceptor 3; P2X purinoceptor 3; P2X purinoceptor 3; purinergic receptor P2X 3; ATP receptor; Purinergic receptor] |
Gene, Accession # | [P2X3], Gene ID: 5024, UniProt: P56373 |
Catalog # | MBS4157615 |
Price | $725 |
Order / More Info | P2X3 Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |