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Antigenic Specificity | EEF1E1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat. |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010] |
Immunogen | Immunogen: Rabbit polyclonal EEF1E1 (1) antibody was raised against a recombinate human EEF1E1 protein 1-174 aa (BC005291). |
Other Names | [eukaryotic translation elongation factor 1 epsilon-1 isoform 2; Eukaryotic translation elongation factor 1 epsilon-1; eukaryotic translation elongation factor 1 epsilon-1; ARS-interacting multifunctional protein 3; aminoacyl tRNA synthetase complex-interacting multifunctional protein 3; multisynthase complex auxiliary component p18; p18 component of aminoacyl-tRNA synthetase complex; eukaryotic translation elongation factor 1 epsilon 1; Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3; Elongation factor p18; Multisynthase complex auxiliary component p18], [EEF1E1; EEF1E1; P18; AIMP3] |
Gene, Accession # | [EEF1E1], Gene ID: 9521, NCBI: NP_001129122.1 |
Catalog # | MBS415695 |
Price | $230 |
Order / More Info | EEF1E1 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Kim,S.S., Hur,S.Y., Kim,Y.R. et al. Expression of AIMP1, 2 and 3, the scaffolds for the multi-tRNA synthetase complex, is downregulated in gastric and colorectal cancer. Tumori 97 (3), 380-385 (2011). |