KANK1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | KANK1 |
| Clone | [1773CT634.49.61] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1,k |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This KANK1 antibody is generated from a mouse immunized with a recombinant protein of human KANK1. Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity; the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia; the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading; the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the |
| Immunogen | n/a |
| Other Names | [KN motif and ankyrin repeat domain-containing protein 1; Ankyrin repeat domain-containing protein 15; Kidney ankyrin repeat-containing protein; KANK1; ANKRD15; KANK; KIAA0172] |
| Gene, Accession # | [KANK1], Gene ID: 23189, NCBI: NP_001243805.1, UniProt: Q14678 |
| Catalog # | MBS9230949 |
| Price | $165, $370 |
| Order / More Info | KANK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Nagase T.,et al.DNA Res. 3:17-24 (1996). Humphray S.J.,et al.Nature 429:369-374 (2004). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Sarkar S.,et al.J. Biol. Chem. 277:36585-36591 (2002). Wang Y.,et al.Biochem. Biophys. Res. Commun. 330:1247-1253 (2005). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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