TAB1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | TAB1 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for TGF-beta-activated kinase 1/MAP3K7-binding protein 1(TAB1) detection. Tested with WB in Human;Rat. Background: Mitogen-activated protein kinase kinase kinase 7-interacting protein 1, also called TAB1, is an enzyme that in humans is encoded by the MAP3K7IP1 gene. It is mapped to 22q13.1. The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways. This protein can interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TAB1 (78-108aa NFVAQRLSAELLLGQLNAEHAEADVRRVLLQ), different from the related mouse sequence by two amino acids. Ig Type: Rabbit IgG |
| Other Names | [TGF-beta-activated kinase 1/MAP3K7-binding protein 1; 2310012M03Rik; 3'-Tab1; MAP3K7IP 1; MAP3K7IP1; MGC57664; Mitogen activated protein kinase kinase kinase 7 interacting protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TAB 1; TAB1; TAK1 binding protein 1; TAK1-binding protein 1; TGF beta activated kinase 1 binding protein 1; TGF-beta activated kinase 1/MAP3K7 binding protein 1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; TGF-beta-activated kinase 1-binding protein 1; Transforming growth factor beta activated kinase binding protein 1; TGF-beta activated kinase 1/MAP3K7 binding protein 1], [TAB1; TAB1; 3'-Tab1; MAP3K7IP1; MAP3K7IP1; TAK1-binding protein 1] |
| Gene, Accession # | [TAB1], Gene ID: 10454, NCBI: NP_006107.1, UniProt: Q15750 |
| Catalog # | MBS178139 |
| Price | $280 |
| Order / More Info | TAB1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: MAP3K7IP1 mitogen-activated protein kinase kinase kinase 7 interacting protein 1 2. Sakurai H, Miyoshi H, Toriumi W, Sugita T (May 1999). Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation. J Biol Chem274 (15): 10641-8. 3. Shibuya, H., Yamaguchi, K., Shirakabe, K., Tonegawa, A., Gotoh, Y., Ueno, N., Irie, K., Nishida, E., Matsumoto, K. TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. Science 272: 1179-1182, 1996. |
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MYBIOSOURCE INC.
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