RIP2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RIP2 |
| Clone | [AF28D3] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1/k |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | 1.0mg/ml |
| Applications | ELISA, Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The RIP (receptor-interacting protein) family of serine/Threonine kinases (RIP-1,2,3,4,5,6,7) are crucial regulators of cell survival and cell death that can trigger pro-survival, inflammatory and immune responses via the activation of transcription factors (NF-kB and AP-1) and death-inducing programs. RIP2 (also known as RICK, CARDIAK, CCK and Ripk2) transduces signals from receptors of both immune responses. RIP2 carries a CARD at its C-terminal, which is essential for NF-kB activation. RIP2 is a critical downstream mediator of Nod1 and Nod2 signaling. Overexpression of RIP2 results in the activation of, in addition to NF-kB, the MAPKs JNK and ERK2, requiring its kinase activity to activate ERK2, but not JNK. |
| Immunogen | Immunogen: Recombinant human protein purified from E Coli |
| Other Names | [RIP2; RIP2; RIPK2; receptor-interacting serine-threonine kinase 2; BOS_14104; CARD3; CARD-carrying kinase; CARD-containing IL-1 beta ICE-kinase; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase; CARDIAK; CCK; D4Bwg0615e; GIG30; growth-inhibiting gene 30; PANDA_012473; RCJMB04_15n4; receptor interacting protein 2; receptor-interacting protein 2; receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; receptor-interacting serine/threonine-protein kinase 2; receptor (TNFRSF)-interacting serine-threonine kinase 2; RICK; RIP2; RIP-2; RIP-like-interacting CLARP kinase; RP23-378L22.1; tyrosine-protein kinase RIPK2; WUGSC:H_RG437L15.1], [RIPK2; RIPK2; CCK; RICK; RIP2; CARD3; GIG30; CARDIAK; CARDIAK; RICK; RIP2; CARD-containing IL-1 beta ICE-kinase; RIP-2] |
| Gene, Accession # | [RIP2], Gene ID: 8767, NCBI: NP_003812.1, UniProt: O43353 |
| Catalog # | MBS832537 |
| Price | $375 |
| Order / More Info | RIP2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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