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Antigenic Specificity | L3MBTL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/HIST1H1E at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at 'Lys-382', leading to repress p53/TP53-target genes. Also recognizes and binds RB1/RB monomethylated at 'Lys-860'. Participates in the ETV6-mediated repression. Probably plays |
Immunogen | Immunogen: Recombinant human Lethal(3)malignant brain tumor-like protein 1 protein (513-752aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-50039 / sc-50040 / sc-50038 / sc-50041 / sc-98449 |
Other Names | [H-l(3)mbt; H-l(3)mbt protein; L(3)mbt-like; L(3)mbt protein homolog; L3MBTL1; KIAA0681; L3MBT; L3MBTL], [L3MBTL1; L3MBTL1; L3MBTL; ZC2HC3; H-L(3)MBT; dJ138B7.3; KIAA0681; L3MBT; L3MBTL; H-l(3)mbt; H-l(3)mbt protein; L(3)mbt-like] |
Gene, Accession # | [L3MBTL1], Gene ID: 26013, NCBI: NP_056293.4, UniProt: Q9Y468 |
Catalog # | MBS1495427 |
Price | $120, $160 |
Order / More Info | L3MBTL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |