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Antigenic Specificity | Human CD18 |
Clone | [YFC118.3] |
Host Species | Rat |
Reactive Species | dog, guinea pig |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.2 mg |
Concentration | IgG concentration 1 mg/ml |
Applications | Immunohistology Frozen*, Flow cytometry (FC/FACS), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti Human CD18 antibody, clone YFC118.3 was clustered at the Fourth International Workshop on Leucocyte Differentiation Antigen (code number N221) as recognising the CD18 antigen. The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight - known as the beta chain, of the LFA-1 complex. The CD18 antigen is non-covalently linked to CD11a, b, c molecules. The main cellular reactivity of Rat anti Human CD18 antibody, clone YFC118.3 is a strong reactivity with Leucocytes (platelets negative). The CD18 molecule is the receptor for ICAM-1 and is thus important for cell adhesion. |
Immunogen | Immunogen: Human neutrophils Histology Positive Control Tissue: Human Tonsil Fusion Partners: Spleen cells from immunised LOU rats were fused with cells of the rat Y3/Ag.1.2.3 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [integrin beta-2; Integrin beta-2; integrin beta-2; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); complement receptor C3 beta-subunit; integrin beta chain, beta 2; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD_antigen: CD18], [ITGB2; ITGB2; LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1; CD18; MFI7] |
Gene, Accession # | [CD18], Gene ID: 3689, NCBI: NP_000202.2, UniProt: P05107 |
Catalog # | MBS213057 |
Price | $430 |
Order / More Info | Human CD18 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |