Edit |   |
---|---|
Antigenic Specificity | Synphilin-1 (SNCAIP) (C-term), 593-622 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Synphilin-1 (SNCAIP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 593-622 amino acids from the C-terminal region of human Synphilin-1 (SNCAIP). Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shows extensive homology with |
Immunogen | n/a |
Other Names | [Synphilin-1; Sph1; Alpha-synuclein-interacting protein; SNCAIP] |
Gene, Accession # | [SNCAIP], Gene ID: 9627, NCBI: NP_001229864.1, UniProt: Q9Y6H5 |
Catalog # | MBS9209537 |
Price | $165, $370 |
Order / More Info | Synphilin-1 (SNCAIP) (C-term), 593-622 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kruger,R. Cell Tissue Res. 318 (1), 195-199 (2004) Lee,G., etal. J. Biol. Chem. 279 (8), 6834-6839 (2004) Tanaka,M., et al. J. Biol. Chem. 279 (6), 4625-4631 (2004) Nagano,Y., et al. J. Biol. Chem. 278 (51), 51504-51514 (2003) Marx,F.P., etal. Hum. Mol. Genet. 12 (11), 1223-1231 (2003) Junn,E., et al. J. Biol. Chem. 277 (49), 47870-47877 (2002) Chung,K.K., et al. Nat. Med. 7 (10), 1144-1150 (2001) Kawamata,H., et al. J. Neurochem. 77 (3), 929-934 (2001) Engelender,S., et al. Nat. Genet. 22 (1), 110-114 (1999) |