PARP1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | PARP1 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PARP (Poly (ADP-ribose) polymerase) is a 113 kDa nuclear protein which can exist as a homo-or hetero-dimer, and is strongly activated by DNA strand breaks. This protein acts as a molecular nick sensor and functions in base excision repair, poly(ADPribosyl)ation of acceptor proteins involved in chromatin architecture and DNA metabolism, and participates in protein modification to enhance or repress transcription. PARP is ribosylated by PARP2, and during apoptosis, ICE family members, such as caspase 3 and 7, cleave PARP to yield an 85 kDa and a 25 kDa fragment. |
| Immunogen | Immunogen: Synthetic peptide corresponding to C-terminus amino acids of PARP1 human protein. Preservative: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4. Cellular Localization: Nucleus |
| Other Names | [Rabbit IgG to PARP1], [PARP11; PARP11; ARTD11; MIB006; C12orf6; C12orf6; PARP-11; ARTD11] |
| Gene, Accession # | [PARP1], Gene ID: 57097, NCBI: NP_065100.2, UniProt: Q9NR21 |
| Catalog # | MBS859081 |
| Price | $280 |
| Order / More Info | PARP1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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