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Antigenic Specificity | CTLA-4 |
Clone | [IHC004] |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Intended Use: The CTLA-4 [IHC004] antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods. Description: Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a receptor on T Helper cells that functions as an immune checkpoint and downregulator of immune responses. Mutations in CTLA-4 are associated with insulin-dependent diabetes mellitus, Hashimoto's thyroiditis, Graves' disease, systemic lupus erythematosus (SLE), celiac disease, primary biliary cirrhosis, thyroid-associated orbitopathy, multiple sclerosis, and other autoimmune diseases. The spliced variant of CTLA-4 in SLE is |
Immunogen | n/a |
Other Names | [cytotoxic T-lymphocyte protein 4 isoform CTLA-4delTM; Cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte associated protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD_antigen: CD152], [CTLA4; CTLA4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; CD152; CTLA-4] |
Gene, Accession # | [CTLA-4], Gene ID: 1493, NCBI: NP_001032720.1, UniProt: P16410 |
Catalog # | MBS344004 |
Price | please inquire |
Order / More Info | CTLA-4 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Denizot F, et al. Nature. 1987; 328:267-70.2. Dariavach P, et al. Eur J Immunol. 1988; 18:1901-5.3. Krummel MF, et al. J Exp Med. 1995; 182:459-65.4. Kuehn HS, et al. Science. 2014; 345:1623-7.5. Walunas TL, et al. J Exp Med. 1996; 183:2541-50. |