XAF1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-XAF1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | XAF1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Seems to function as a negative regulator of members of the IAP (inhibitor of apoptosis protein) family. Inhibits anti-caspase activity of BIRC4. Induces cleavage and inactivation of BIRC4 independent of caspase activation. Mediates TNF-alpha-induced apoptosis and is involved in apoptosis in trophoblast cells. May inhibit BIRC4 indirectly by activating the mitochondrial apoptosis pathway. After translocation to mitochondra, promotes translocation of BAX to mitochondria and cytochrome c release from mitochondria. Seems to promote the redistribution of BIRC4 from the cytoplasm to the nucleus, probably independent of BIRC4 inactivation which seems to occur in the cytoplasm. The BIRC4-XAF1 complex mediates down-regulation of BIRC5/survivin; the |
| Immunogen | Immunogen: Recombinant Human XIAP-associated factor 1 protein (172-259AA) |
| Other Names | [XIAP-associated factor 1; BIRC4-binding protein; XAF1; BIRC4BP; XIAPAF1] |
| Gene, Accession # | [XAF1], Gene ID: 54739, NCBI: NP_059993.2, UniProt: Q6GPH4 |
| Catalog # | MBS7050551 |
| Price | $160, $235 |
| Order / More Info | XAF1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies