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Antigenic Specificity | POU2F1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Oct-1 (POU2F1) is a ubiquitously expressed, octamer-binding transcription factor containing a POU domain with a homeobox subdomain (1). Oct-1 has been shown to interact with several transcription factors in mediating specific gene expression, including SNAPc (2), OBF-1 (a B-cell transcriptional coactivator protein) (3), TFIIB (4), and TBP (TATA-box-binding protein) (5). Its POU DNA-binding domain allows Oct-1 the flexibility to facilitate the binding and recruitment of several tissue-specific cofactors to either positively or negatively regulate a variety of genes, exerting an important role in development (6). |
Immunogen | Immunogen: Recombinant protein of human POU2F1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [OCT1; OTF1] |
Gene, Accession # | [POU2F1], Gene ID: 5451, NCBI: NP_001185712.1, UniProt: P14859 |
Catalog # | MBS8501472 |
Price | $310 |
Order / More Info | POU2F1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Sturm, R.A. et al. (1988) Genes Dev 2, 1582-99. 2. Mittal, V. et al. (1996) Mol Cell Biol 16, 1955-65. 3. Strubin, M. et al. (1995) Cell 80, 497-506. 4. Nakshatri, H. et al. (1995) J Biol Chem 270, 19613-23. 5. Zwilling, S. et al. (1994) Nucleic Acids Res 22, 1655-62. 6. Schonemann, M.D. et al. (1998) Adv Exp Med Biol 449, 39-53. |