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Antigenic Specificity | PIP4K2A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. May be involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-350 of human PIP4K2A (NP 005019.2). |
Other Names | [PIPK; PI5P4KA; PIP5K2A; PIP5KIIA; PIP5KII-alpha] |
Gene, Accession # | [PIP4K2A], Gene ID: 5305, NCBI: NP_005019.2, UniProt: P48426 |
Catalog # | MBS8546819 |
Price | $280 |
Order / More Info | PIP4K2A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |