Edit |   |
---|---|
Antigenic Specificity | UBE1L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: UBE1L Polyclonal Antibody detects endogenous levels of UBE1L protein. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 pr |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human UBE1L at AA range: 940-1020 |
Other Names | [Rabbit UBE1L; UBA7; UBE1L; UBE2; Ubiquitin-like modifier-activating enzyme 7; Ubiquitin-activating enzyme 7; D8; Ubiquitin-activating enzyme E1 homolog] |
Gene, Accession # | [UBE1L], Gene ID: 7318, NCBI: NP_003326.2, UniProt: P41226 |
Catalog # | MBS9703330 |
Price | $130, $220, $325 |
Order / More Info | UBE1L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |