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Antigenic Specificity | SATB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SATB1 Antibody: Human special AT-rich sequence-binding protein-1 (SATB1) is a nuclear matrix/scaffold-associated region DNA-binding protein, predominantly expressed in the thymus and pre-B cells. Like its homolog SATB2, SATB1 selectively binds double-stranded, special AT-rich DNA sequences in which one strand exclusively consists of well-mixed A, T, and C nucleotides. SATB1 contains a dimerization domain that shares similarity with the PDZ motif, identified as an indispensable element for high-affinity binding of SATB1 to DNA. SATB1 constitutes a functional nuclear architecture that has a 'cage-like' protein distribution surrounding heterochromatin and regulates gene expression through chromatin remodeling/HDAC (histone deacetylase complex) |
Immunogen | Immunogen: SATB1 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of the human SATB1. Buffer: SATB1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [SATB1; DNA-binding protein SATB1; Special AT-rich sequence-binding protein 1; SATB homeobox 1], [SATB1; SATB1] |
Gene, Accession # | [SATB1], Gene ID: 6304, NCBI: Q01826.1, UniProt: Q01826 |
Catalog # | MBS150491 |
Price | $375 |
Order / More Info | SATB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |