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Antigenic Specificity | SMARCA5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity. Complexes containing SMARCA5 are capable of forming ordered nucleosome arrays on chromatin; this may require intact histone H4 tails. Also required for replication of pericentric heterochromatin in S-phase specifically in conjunction with BAZ1A. Probably plays a role in repression of polI dependent transcription of the rDNA locus, through the recruitment of the SIN3/HDAC1 corepressor complex to the rDNA promoter. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role i |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human SMARCA5 (NP 003592.3). |
Other Names | [ISWI; SNF2H; hISWI; hSNF2H; WCRF135] |
Gene, Accession # | [SMARCA5], Gene ID: 8467, NCBI: NP_003592.3, UniProt: O60264 |
Catalog # | MBS8544730 |
Price | $280 |
Order / More Info | SMARCA5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |