CASP3 - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCASP3 - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, porcine, rabbit, rat
Isotypen/a
FormatProtein A purified
Size0.1 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against CASP3. It was validated on Western Blot using a cell lysate as a positive control.Target Description: CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CASP3
Other Names[caspase-3 isoform a preproprotein; Caspase-3; caspase-3; caspase 3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1]
Gene, Accession #[CASP3], Gene ID: 836, NCBI: NP_004337, UniProt: P42574
Catalog #MBS3224317
Price$290
Order / More InfoCASP3 - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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