Phospho-CREB-Ser133 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Phospho-CREB-Ser133 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CREB is a bZIP transcription factor that activates target genes through cAMP response elements. CREB is able to mediate signals from numerous physiological stimuli, resulting in regulation of a broad array of cellular responses. While CREB is expressed in numerous tissues, it plays a large regulatory role in the nervous system. CREB is believed to play a key role in promoting neuronal survival, precursor proliferation, neurite outgrowth, and neuronal differentiation in certain neuronal populations (1-3). Additionally, CREB signaling is involved in learning and memory in several organisms (4-6). CREB is able to selectively activate numerous downstream genes through interactions with different dimerization partners. CREB is activated by phosp |
| Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Ser133 of human CREB Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [CREB1; CREB; MGC9284] |
| Gene, Accession # | [CREB], Gene ID: 1385, NCBI: NP_004370.1, UniProt: P16220 |
| Catalog # | MBS8527416 |
| Price | $310 |
| Order / More Info | Phospho-CREB-Ser133 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Lonze, B.E. et al. (2002) Neuron 34, 371-85. 2. Lee, M.M. et al. (1999) J Neurosci Res 55, 702-12. 3. Redmond, L. et al. (2002) Neuron 34, 999-1010. 4. Dash, P.K. et al. (1990) Nature 345, 718-21. 5. Yin, J.C. et al. (1994) Cell 79, 49-58. 6. Guzowski, J.F. and McGaugh, J.L. (1997) Proc Natl Acad Sci USA 94, 2693-8. 7. Xing, J. et al. (1998) Mol Cell Biol 18, 1946-55. 8. Ribar, T.J. et al. (2000) J Neurosci 20, RC107. 9. Tan, Y. et al. (1996) EMBO J 15, 4629-42. |
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MYBIOSOURCE INC.
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