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Antigenic Specificity | IPO4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IPO4 antibody detects endogenous levels of IPO4. Function: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distri |
Immunogen | Immunogen: A synthesized peptide derived from human IPO4. Subcellular Location: Cytoplasm. Nucleus. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (92%), Rabbit (100%), Dog (100%) |
Other Names | [Imp4; Imp4b; Importin 4; Importin 4b; Importin-4; Importin-4b; Ipo4; IPO4_HUMAN; Ran binding protein 4; Ran-binding protein 4; RanBP4] |
Gene, Accession # | [IPO4], Gene ID: 79711, NCBI: NP_078934.3, UniProt: Q8TEX9 |
Catalog # | MBS9603435 |
Price | $240, $280 |
Order / More Info | IPO4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |