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Antigenic Specificity | Phospho-EIF2AK2-T451 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding T451 of human EIF2AK2 Calculated Molecular Weight: 68kDa |
Other Names | [Phospho-EIF2AK2-T451: PKR; PRKR; EIF2AK1], [EIF2AK2; EIF2AK2; PKR; PRKR; EIF2AK1; PPP1R83; eIF-2A protein kinase 2; PKR; Protein kinase R] |
Gene, Accession # | [EIF2AK2], Gene ID: 5610, NCBI: P19525.2, UniProt: P19525 |
Catalog # | MBS128279 |
Price | $235, $350, $525 |
Order / More Info | Phospho-EIF2AK2-T451 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |