TFRC Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTFRC
Clone[1A1B2]
Host SpeciesMouse
Reactive Specieshuman, mouse, monkey, rat
IsotypeIgG1
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA)
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DescriptionTransferrin receptor is a carrier protein for transferrin. It is needed for the import of iron into the cell and is regulated in response to intracellular iron concentration. Low iron concentrations promote increased levels of transferrin receptor, to increase iron intake into the cell. Thus, transferrin receptor maintains cellular iron homeostasis. Expression of human TFR1, but not human TFR2, in hamster cell lines markedly enhanced the infection of viruses pseudotyped with the glycoprotein of Machupo, Guanarito, and Junin viruses, but not with those of Lassa or lymphocytic choriomeningitis viruses. An anti-TFR1 antibody efficiently inhibited the replication of Machupo, Guanarito, Junin, and Sabia viruses, but not that of Lassa virus.TFR1
ImmunogenImmunogen: Purified recombinant fragment of human TFRC (AA: 608-727) expressed in E. Coli.
Other Names[T9; TR; TFR; p90; CD71; TFR1; TRFR]
Gene, Accession #[TFRC], Gene ID: 7037, NCBI: NP_001121620.1, UniProt: P02786
Catalog #MBS8539081
Price$280
Order / More InfoTFRC Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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