Phospho-TICAM2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-TICAM2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentration0.50-0.75 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionAffinity Purified Phosphorylated TRIF-related adapter molecule Antibody. Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4.
ImmunogenImmunogen: Phosphorylated synthetic peptide corresponding to unique amino acid sequences on TRIF-related adapter molecule protein. Expression: Expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas Isoform 2 is ubiquitously expressed (at lower levels than isoform 1).
Other Names[Putative NF-kappa-B-activating protein 502; TIR containing adapter molecule 2; TIR domain containing adaptor protein; TIRAP3; TIRP; Toll-like receptor adaptor protein 3; Toll/interleukin-1 receptor domain-containing protein; TRAM; TRIF-related adapter molecule], [TICAM2; TICAM2; TIRP; TRAM; TIRAP3; MyD88-4; TICAM-2; TIRAP3; TIRP; TRAM; TICAM-2; MyD88-4]
Gene, Accession #[TICAM2], Gene ID: 353376, NCBI: AAO74498.1, UniProt: Q86XR7
Catalog #MBS540511
Price$495
Order / More InfoPhospho-TICAM2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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