DDR2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDDR2
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: DDR2 antibody detects endogenous levels of total DDR2. Description: DDR2 (discoidin domain receptor family, member 2) is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. T
ImmunogenImmunogen: Purified recombinant fragment of human DDR2 expressed in E. Coli Subcellular Location: Membrane. Tissue Specificity: Detected in osteocytes, osteoblastic cells in subchondral bone, bone lining cells, tibia and cartilage (at protein level). Detected at high levels in heart and lung, and at low levels in brain, placenta, liver, skeletal muscle, pancreas, and kidney.
Other Names[CD167 antigen-like family member B; CD167b; CD167b antigen; Cell migration inducing protein 20; DDR 2; DDR2; DDR2_HUMAN; Discoidin domain containing receptor 2; Discoidin domain receptor 2; Discoidin domain receptor family member 2; discoidin domain receptor tyrosine kinase 2; Discoidin domain-containing receptor 2; discoidin domain-containing receptor tyrosine kinase 2; Hydroxyaryl protein kinase; MIG20a; Migration inducing gene 16 protein; Neurotrophic tyrosine kinase; Neurotrophic tyrosine kinase receptor related 3; NTRKR 3; NTRKR3; Receptor protein tyrosine kinase TKT; Receptor protein-tyrosine kinase TKT; Receptor related 3; receptor-related 3; TKT; TYRO 10; TYRO10; Tyrosine kinase receptor related to neurotrophic TRK; Tyrosine protein kinase TYRO 10; Tyrosine protein kinase TYRO10; Tyrosine-protein kinase TYRO10; Tyrosylprotein kinase]
Gene, Accession #[DDR2], Gene ID: 4921, NCBI: NP_001014796.1, UniProt: Q16832
Catalog #MBS9602631
Price$235, $295, $370
Order / More InfoDDR2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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