Phospho PKC eta (S6 & S10) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho PKC eta (S6 & S10)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatbiotin conjugate
Size0.1 mg
Concentration0.7 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), IMM, Western Blot (WB)
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DescriptionBIOTIN-Conjugated Phosphorylated PKC eta S6 & S10 Antibody N-epitope. Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentiation. Inhibits CDK2 kinase activity, leading to RB1 dephosphorylation and thereby G1 arrest in keratinocytes. In ass
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 1-50 on human PKC eta protein. Phosphorylated S28 & S32. Expression: Most abundant in lung, less in heart and skin.
Other Names[MGC 5363; MGC26269; MGC5363; PKC L; PRKCH; PRKCL; Protein kinase C eta type], [PRKCH; PRKCH; PKCL; PKC-L; PRKCL; nPKC-eta; PKCL; PRKCL]
Gene, Accession #[PKC], Gene ID: 5583, NCBI: NP_006246, UniProt: P24723
Catalog #MBS544278
Price$550
Order / More InfoPhospho PKC eta (S6 & S10) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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