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Antigenic Specificity | Phospho PKC eta (S6 & S10) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.1 mg |
Concentration | 0.7 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), IMM, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BIOTIN-Conjugated Phosphorylated PKC eta S6 & S10 Antibody N-epitope. Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentiation. Inhibits CDK2 kinase activity, leading to RB1 dephosphorylation and thereby G1 arrest in keratinocytes. In ass |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 1-50 on human PKC eta protein. Phosphorylated S28 & S32. Expression: Most abundant in lung, less in heart and skin. |
Other Names | [MGC 5363; MGC26269; MGC5363; PKC L; PRKCH; PRKCL; Protein kinase C eta type], [PRKCH; PRKCH; PKCL; PKC-L; PRKCL; nPKC-eta; PKCL; PRKCL] |
Gene, Accession # | [PKC], Gene ID: 5583, NCBI: NP_006246, UniProt: P24723 |
Catalog # | MBS544278 |
Price | $550 |
Order / More Info | Phospho PKC eta (S6 & S10) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |