PARN - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPARN - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThe protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human PARN
Other Names[poly(A)-specific ribonuclease PARN isoform 2; Poly(A)-specific ribonuclease PARN; poly(A)-specific ribonuclease PARN; poly(A)-specific ribonuclease; Deadenylating nuclease; Deadenylation nuclease; Polyadenylate-specific ribonuclease]
Gene, Accession #[PARN], Gene ID: 5073, NCBI: NP_001127949.1, UniProt: O95453
Catalog #MBS3219797
Price$335
Order / More InfoPARN - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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