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Antigenic Specificity | PARN - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PARN |
Other Names | [poly(A)-specific ribonuclease PARN isoform 2; Poly(A)-specific ribonuclease PARN; poly(A)-specific ribonuclease PARN; poly(A)-specific ribonuclease; Deadenylating nuclease; Deadenylation nuclease; Polyadenylate-specific ribonuclease] |
Gene, Accession # | [PARN], Gene ID: 5073, NCBI: NP_001127949.1, UniProt: O95453 |
Catalog # | MBS3219797 |
Price | $335 |
Order / More Info | PARN - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |