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Antigenic Specificity | NTRK1 |
Clone | [185CT47.6.1] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1,k |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This NTRK1 Monoclonal antibody was raised using purified His-tagged recombinant human NTRK1. This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
Immunogen | n/a |
Other Names | [High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A; Trk-A; gp140trk; p140-TrkA; NTRK1; MTC; TRK; TRKA] |
Gene, Accession # | [NTRK1], Gene ID: 4914, NCBI: NP_001007793.1, UniProt: P04629 |
Catalog # | MBS9200013 |
Price | $370 |
Order / More Info | NTRK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Li, C., et al. Clin. Chim. Acta 411 (19-20), 1482-1486 (2010) : Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Brahimi, F., et al. Biochim. Biophys. Acta 1800(9):1018-1026(2010) Rao, R., et al. Mol. Cancer Ther. 9(8):2232-2242(2010) Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) : |