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Antigenic Specificity | Phospho-CFL1-Y139 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Phospho-CFL1-Y139 antibody. The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y139 of human CFL1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | n/a |
Gene, Accession # | [CFL1-Y139] |
Catalog # | MBS4153067 |
Price | $510 |
Order / More Info | Phospho-CFL1-Y139 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |