PP2C-alpha Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PP2C-alpha |
| Clone | [1D2-E6-F2] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Entrez Summary: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript v |
| Immunogen | Immunogen: Purified recombinant fragment of human PPM1A (AA: 202-382) expressed in E Coli. Sequence Similarities: Contains 1 PPM-type phosphatase domain. |
| Other Names | [Protein phosphatase 2C isoform alpha; EC 3.1.3.16; FLJ42306; IA; MGC9201; Mpp alpha; PP2C alpha; PP2C-alpha; PP2CA; PP2Calpha; PPM 1A; PPM1A; PPM1A_HUMAN; PPPM1A; Protein phosphatase 1A (formerly 2C) magnesium dependent alpha isoform; Protein phosphatase 1A; Protein phosphatase 1A magnesium dependent alpha; Protein phosphatase 2C alpha; Protein phosphatase 2C alpha isoform; Protein phosphatase 2C isoform alpha; Protein phosphatase IA; Protein phosphatase, Mg2+/Mn2+ dependent, 1A], [PPM1A; PP2CA; PP2Calpha; PP2C-ALPHA] |
| Gene, Accession # | [PP2C-alpha], Gene ID: 5494, NCBI: NP_066283.1, UniProt: P35813 |
| Catalog # | MBS476313 |
| Price | $335 |
| Order / More Info | PP2C-alpha Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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