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Antigenic Specificity | PCBP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PCBP1 protein. This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. PCBP1 and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication |
Immunogen | Immunogen: Synthesized peptide derived from part region of human PCBP1 protein at amino acid sequence of 30-110 |
Other Names | [Rabbit PCBP1; Poly(rC)-binding protein 1; Alpha-CP1; Heterogeneous nuclear ribonucleoprotein E1; Nucleic acid-binding protein SUB2.3; hnRNP E1] |
Gene, Accession # | [PCBP1], Gene ID: 5093, NCBI: NP_006187.2, UniProt: Q15365 |
Catalog # | MBS9710392 |
Price | $130, $220, $325 |
Order / More Info | PCBP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |