Edit |   |
Antigenic Specificity | SNX3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SNX3 antibody detects endogenous levels of total SNX3. Function: Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Also can bind phosphatidylinositol 4-phosphate (PtdIns(P4)), phosphatidylinositol 5-phosphate (PtdIns(P5)) and phosphatidylinositol 3, 5-biphosphate (PtdIns(3, 5)P2) (By similarity). Plays a role in protein transport between cellular compartments. Together with RAB7A facilitates endosome membrane association of the retromer cargo-selective subcomplex (CSC/VPS). May in part act as component of the SNX3-retromer complex which mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway ( |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Early Endosome. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (82%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (82%), Xenopus (91%) |
Other Names | [Grd19; MCOPS8; MGC151262; MGC151266; MGC17570; OTTHUMP00000016941; OTTHUMP00000046475; OTTHUMP00000046476; Protein SDP3; SDP3; SNX3; SNX3_HUMAN; SNX3A; Sorting nexin 3; Sorting nexin 3A; Sorting nexin-3] |
Gene, Accession # | [SNX3], Gene ID: 8724, NCBI: NP_001287858.1, UniProt: O60493 |
Catalog # | MBS9605991 |
Price | $240, $280 |
Order / More Info | SNX3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |