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Antigenic Specificity | CENPJ |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. Alternatively spliced transcript variants have been found for this gene. |
Immunogen | Immunogen: Recombinant protein of human CENPJ (NP 060921.3). |
Other Names | [centromere protein J; Centromere protein J; centromere protein J; centromere protein J; Centrosomal P4.1-associated protein; LAG-3-associated protein; LYST-interacting protein 1] |
Gene, Accession # | [CENPJ], Gene ID: 55835, NCBI: NP_060921.3, UniProt: Q9HC77 |
Catalog # | MBS8574088 |
Price | $280 |
Order / More Info | CENPJ Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |