PACS2-Specific Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPACS2-Specific
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: PACS2-Specific antibody detects endogenous levels of PACS2-Specific. Function: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.Subunit Structure: Interacts with BID and PKD2 (PubMed:15692567, PubMed:15692563).
ImmunogenImmunogen: A synthesized peptide derived from human PACS2-Specific. Subcellular Location: Endoplasmic Reticulum Lumen. Mitochondrion. Tissue Specificity: Broadly expressed, with greatest levels in skeletal muscle followed by heart, brain, pancreas and testis. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%)
Other Names[6720425G15Rik; AW208651; AW489976; E230011J22; FLJ25488; KIAA0602; mKIAA0602; PACS 2; PACS-2; PACS1 like protein; PACS1-like protein; PACS1L; PACS2; PACS2_HUMAN; Phosphofurin acidic cluster sorting protein 1 like; Phosphofurin acidic cluster sorting protein 2]
Gene, Accession #[PACS2], Gene ID: 23241, NCBI: NP_001094383.2, UniProt: Q86VP3
Catalog #MBS9603669
Price$240, $280
Order / More InfoPACS2-Specific Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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