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Antigenic Specificity | PACS2-Specific |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PACS2-Specific antibody detects endogenous levels of PACS2-Specific. Function: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.Subunit Structure: Interacts with BID and PKD2 (PubMed:15692567, PubMed:15692563). |
Immunogen | Immunogen: A synthesized peptide derived from human PACS2-Specific. Subcellular Location: Endoplasmic Reticulum Lumen. Mitochondrion. Tissue Specificity: Broadly expressed, with greatest levels in skeletal muscle followed by heart, brain, pancreas and testis. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%) |
Other Names | [6720425G15Rik; AW208651; AW489976; E230011J22; FLJ25488; KIAA0602; mKIAA0602; PACS 2; PACS-2; PACS1 like protein; PACS1-like protein; PACS1L; PACS2; PACS2_HUMAN; Phosphofurin acidic cluster sorting protein 1 like; Phosphofurin acidic cluster sorting protein 2] |
Gene, Accession # | [PACS2], Gene ID: 23241, NCBI: NP_001094383.2, UniProt: Q86VP3 |
Catalog # | MBS9603669 |
Price | $240, $280 |
Order / More Info | PACS2-Specific Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |