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Antigenic Specificity | PRIC285 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PRIC285 antibody detects endogenous levels of total PRIC285. Function: Helicase that acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA.Subunit Structure: Interacts with PPARA (via DNA-binding domain) and PPARG; the interaction stimulates the transcriptional activity of PPARA and PPARG. Interacts with THRAP3; the interaction is direct and HELZ2 and THRAP3 synergistically enhance the transcriptional activity of PPARG. It is probably part of the peroxisome proliferator activated receptor alpha interacting complex (PRIC).Similarity: Contains 5 Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs. These motifs are not required for interaction with PPARG. Belongs to the DNA2/NAM |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Tissue Specificity: Expressed in various tissues including heart, pancreas, skeletal muscle, colon, spleen, liver, kidney, lung, peripheral blood and placenta. |
Other Names | [ATP-dependent helicase PRIC285; KIAA1769; PDIP1; Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein; PPAR-alpha-interacting complex protein 285; PPAR-gamma DBD-interacting protein 1; PPAR-gamma DNA-binding domain-interacting protein 1; PR285_HUMAN; PRIC285; PRPF8] |
Gene, Accession # | [PRIC285], Gene ID: 85441, NCBI: NP_001032412.2, UniProt: Q9BYK8 |
Catalog # | MBS9605739 |
Price | $240, $280 |
Order / More Info | PRIC285 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |