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Antigenic Specificity | PPAR-alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PPAR-alpha antibody detects endogenous levels of total PPAR-alpha. Function: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by P |
Immunogen | Immunogen: A synthesized peptide derived from human PPAR-alpha Subcellular Location: Nucleus. Tissue Specificity: Skeletal muscle, liver, heart and kidney. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Bovine (100%), Horse (88%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (100%) |
Other Names | [hPPAR; MGC2237; MGC2452; NR1C1; Nuclear receptor subfamily 1 group C member 1; OTTHUMP00000197740; OTTHUMP00000197741; Peroxisome proliferative activated receptor alpha; Peroxisome proliferator activated receptor alpha; Peroxisome proliferator-activated receptor alpha; PPAR; PPAR-alpha; ppara; PPARA_HUMAN; PPARalpha] |
Gene, Accession # | [PPARA], Gene ID: 5465, NCBI: NP_001001928.1, UniProt: Q07869 |
Catalog # | MBS9601473 |
Price | $240, $280 |
Order / More Info | PPAR-alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |