Phospho-Ataxin 1 (Ser775) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-Ataxin 1 (Ser775) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-Ataxin 1 (Ser775) antibody detects endogenous levels of Ataxin 1 only when phosphorylated at Serine 775. Description: Ataxin-1 is a spinocerebellar ataxia type 1 (SCA1) protein. Expansion of CAG repeats in the SCA1 gene results in an abnormally long polyglutamine tract in the protein, causing polyglutamine-induced neurodegeneration.Function: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism (PubMed:21475249). In concert with CIC and ATXN1L, involved in brain development (By similarity).Subuni |
| Immunogen | Immunogen: A synthesized peptide derived from human Ataxin 1 around the phosphorylation site of Serine 775 Subcellular Location: Cytoplasm. Nucleus. Colocalizes with USP7 in the nucleus. Tissue Specificity: Widely expressed throughout the body. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (89%), Horse (89%), Sheep (89%), Rabbit (89%), Dog (89%), Chicken (100%) |
| Other Names | [alternative ataxin1; Ataxin-1; ATX1; ATX1_HUMAN; Atxn1; D6S504E; OTTHUMP00000016065; SCA1; Spinocerebellar ataxia type 1 protein] |
| Gene, Accession # | [ATXN1], Gene ID: 6310, NCBI: NP_000323.2, UniProt: P54253 |
| Catalog # | MBS9601116 |
| Price | $240, $280 |
| Order / More Info | Phospho-Ataxin 1 (Ser775) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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